The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct.

Evidence suggests that psychedelics bring about their therapeutic outcomes in part through the subjective or qualitative effects they engender and how the individual interprets the resulting experiences. However, psychedelics are contraindicated for individuals who have been diagnosed with certain mental illnesses, on the grounds that these subjective effects may be disturbing or otherwise counter-therapeutic. Substantial resources are therefore currently being devoted to creating psychedelic substances that produce many of the same biological changes as psychedelics, but without their characteristic subjective effects. (...) In this article, we consider ethical issues arising from the prospect of such potential “nonsubjective” psychedelics. We are broadly supportive of efforts to produce such substances for both scientific and clinical reasons. However, we argue that such nonsubjective psychedelics should be reserved for those special cases in which the subjective effects of psychedelics are specifically contraindicated, whereas classic psychedelics that affect subjective experience should be considered the default and standard of care. After reviewing evidence regarding the subjective effects of psychedelics, we raise a number of ethical concerns around the prospect of withholding such typically positive, meaningful, and therapeutic experiences from most patients. (shrink)

Public health and service delivery programmes, interventions and policies are typically developed and implemented for the primary purpose of effecting change rather than generating knowledge. Nonetheless, evaluations of these programmes may produce valuable learning that helps determine effectiveness and costs as well as informing design and implementation of future programmes. Such studies might be termed ‘opportunistic evaluations’, since they are responsive to emergent opportunities rather than being studies of interventions that are initiated or designed by researchers. However, current ethical guidance (...) and registration procedures make little allowance for scenarios where researchers have played no role in the development or implementation of a programme, but nevertheless plan to conduct a prospective evaluation. We explore the limitations of the guidance and procedures with respect to opportunistic evaluations, providing a number of examples. We propose that one key missing distinction in current guidance is moral responsibility: researchers can only be held accountable for those aspects of a study over which they have control. We argue that requiring researchers to justify an intervention, programme or policy that would occur regardless of their involvement prevents or hinders research in the public interest without providing any further protections to research participants. We recommend that trial consent and ethics procedures allow for a clear separation of responsibilities for the intervention and the evaluation. (shrink)

People live and age together in social groups. Across a range of outcomes, research has identified interdependence in the cognitive and health trajectories of ageing couples. Various types of memory decline with age and people report using a range of internal and external, social, and material strategies to compensate for these declines. While memory compensation strategies have been widely studied, research so far has focused only on single individuals. We examined interdependence in the memory compensation strategies reported by spouses within (...) 58 older couples. Couples completed the Memory Compensation Questionnaire, as well as an open-ended interview about their memory compensation practices. We found that internal, intra-individual memory compensation strategies were not associated within couples, but external, extra-individual strategies showed interdependence. Individuals’ scores on material/technological compensation strategies were positively correlated with their partners’. Reported reliance on a spouse was higher for men and increased with age. Our open-ended interviews yielded rich insights into the complex and diverse resources that couples use to support memory in day-to-day life. Particularly evident was the extent of interaction and coordination between social and material compensation, such that couples jointly used external compensation resources. Our results suggest that individuals’ reports of their compensation strategies do not tell the whole story. Rather, we propose that older couples show interdependence in their memory compensation strategies, and adopt complex systems of integrated material and social memory compensation in their day-to-day lives. (shrink)

Vigorous debate over the moral propriety of cognitive enhancement exists, but the views of the public have been largely absent from the discussion. To address this gap in our knowledge, four experiments were carried out with contrastive vignettes in order to obtain quantitative data on public attitudes towards cognitive enhancement. The data collected suggest that the public is sensitive to and capable of understanding the four cardinal concerns identified by neuroethicists, and tend to cautiously accept cognitive enhancement even as they (...) recognize its potential perils. The public is biopolitically moderate, endorses both meritocratic principles and the intrinsic value of hard work, and appears to be sensitive to the salient moral issues raised in the debate. Taken together, these data suggest that public attitudes toward enhancement are sufficiently sophisticated to merit inclusion in policy deliberations, especially if we seek to align public sentiment and policy. (shrink)

The title of this work may seem to beg an important question, since it rests on the assumption that Diderot has a 'concept of physical energy'. Indeed the aim of the study is, in part, to assemble evidence in support of the acte de foi implicit in its title. I am using 'physical energy' in a loose sense, as a convenient term to denote 'what matter can do' as distinct from 'what matter is made of'. Hence it may be taken (...) as broadly synonymous with 'power' or 'force', encompassing both active and potential forms, and thus corresponding to a combination of the fourth and fifth senses identified by the Oxford English Dictionary: 4. Power actively and efficiently displayed or exerted. 5. Power not necessarily manifested in action; ability or capacity to produce an effect. Modern subatomic physics, of course, recognises no such distinction between 'being' and 'doing'; at a fundamental level, matter-as-substance and matter-as-energy are interchangeable (and, as I shall argue towards the end of the study, Diderot himself comes close to a similar position). Nevertheless, the division is both justifiable and useful within the context of eighteenth-century philosophies of nature. For, as many scholars have pointed out, the trend towards nature as an integrated, active phenomenon, in place of the cartesian view of passive tendue only incidentally endowed with motion, was crucial to the development of scientific thought in the mid-eighteenth century. Debate and development on such issues as Newtonian attraction, inertia, electricity and magnetism, chemical reactions, not only contributed directly to the advancement of physics and chemistry, but also (like cartesian mechanism) impinged upon the perennial biological questions, themselves being investigated from a new and exciting angle. As a philosopher rather than a practising scientist, Diderot was ideally placed to draw freely and creatively on all these areas, and his speculations on what we might call 'the nature of nature' are highly characteristic of the new approach. He comes increasingly to discuss and define natural phenomena (organic and inorganic alike) from the point of view of nature's powers - in the spirit of Renaissance naturalism, but from the perspective of up-to-date scientific findings. It is in this sense that I refer to a 'concept of physical energy'. Given the organic quality of Diderot's thought, it is not surprising to find the idea of energy recurring in other areas of his works. If man is composed of matter - active matter - than all human activity, be it moral, political, aesthetic, becomes capable of interpretation in terms of energy. I share Chouillet's conviction that this is a crucial aspect of Diderot's overall philosophy, which deserves to be more widely recognised and more fully understood. (shrink)

Objectives To conduct an independent evaluation of the first phase of the Health Foundation’s Safer Patients Initiative (SPI), and to identify the net additional effect of SPI and any differences in changes in participating and non-participating NHS hospitals. Design Mixed method evaluation involving five substudies, before and after design. Setting NHS hospitals in the United Kingdom. Participants Four hospitals (one in each country in the UK) participating in the first phase of the SPI (SPI1); 18 control hospitals. Intervention The SPI1 (...) was a compound (multi-component) organisational intervention delivered over 18 months that focused on improving the reliability of specific frontline care processes in designated clinical specialties and promoting organisational and cultural change. Results Senior staff members were knowledgeable and enthusiastic about SPI1. There was a small (0.08 points on a 5 point scale) but significant (P<0.01) effect in favour of the SPI1 hospitals in one of 11 dimensions of the staff questionnaire (organisational climate). Qualitative evidence showed only modest penetration of SPI1 at medical ward level. Although SPI1 was designed to engage staff from the bottom up, it did not usually feel like this to those working on the wards, and questions about legitimacy of some aspects of SPI1 were raised. Of the five components to identify patients at risk of deterioration—monitoring of vital signs (14 items); routine tests (three items); evidence based standards specific to certain diseases (three items); prescribing errors (multiple items from the British National Formulary); and medical history taking (11 items)—there was little net difference between control and SPI1 hospitals, except in relation to quality of monitoring of acute medical patients, which improved on average over time across all hospitals. Recording of respiratory rate increased to a greater degree in SPI1 than in control hospitals; in the second six hours after admission recording increased from 40% (93) to 69% (165) in control hospitals and from 37% (141) to 78% (296) in SPI1 hospitals (odds ratio for “difference in difference” 2.1, 99% confidence interval 1.0 to 4.3; P=0.008). Use of a formal scoring system for patients with pneumonia also increased over time (from 2% (102) to 23% (111) in control hospitals and from 2% (170) to 9% (189) in SPI1 hospitals), which favoured controls and was not significant (0.3, 0.02 to 3.4; P=0.173). There were no improvements in the proportion of prescription errors and no effects that could be attributed to SPI1 in non-targeted generic areas (such as enhanced safety culture). On some measures, the lack of effect could be because compliance was already high at baseline (such as use of steroids in over 85% of cases where indicated), but even when there was more room for improvement (such as in quality of medical history taking), there was no significant additional net effect of SPI1. There were no changes over time or between control and SPI1 hospitals in errors or rates of adverse events in patients in medical wards. Mortality increased from 11% (27) to 16% (39) among controls and decreased from 17% (63) to 13% (49) among SPI1 hospitals, but the risk adjusted difference was not significant (0.5, 0.2 to 1.4; P=0.085). Poor care was a contributing factor in four of the 178 deaths identified by review of case notes. The survey of patients showed no significant differences apart from an increase in perception of cleanliness in favour of SPI1 hospitals. Conclusions The introduction of SPI1 was associated with improvements in one of the types of clinical process studied (monitoring of vital signs) and one measure of staff perceptions of organisational climate. There was no additional effect of SPI1 on other targeted issues nor on other measures of generic organisational strengthening. (shrink)

Upcoming responses in the second of two subsequently performed tasks can speed up compatible responses in the temporally preceding first task. Two experiments extend previous demonstration of such backward compatibility to affective features: responses to affective stimuli were faster in Task 1 when an affectively compatible response effect was anticipated for Task 2. This emotional backward-compatibility effect demonstrates that representations of the affective consequences of the Task 2 response were activated before the selection of a response in Task 1 was (...) completed. This finding is problematic for the assumption of a serial stimulus-response translation stage. It also shows that the affective consequence of a response is anticipated during, and has an impact on stimulus-response translation, which implies that action planning considers codes representing and predicting the emotional consequences of actions. Implications for the control of emotional actions are discussed. (shrink)

Purpose – To review and discuss Luciano Floridi’s 2019 book The Logic of Information: A Theory of Philosophy as Conceptual Design, the latest instalment in his philosophy of information (PI) tetralogy, particularly with respect to its implications for library and information studies (LIS). Design/methodology/approach – Nine scholars with research interests in philosophy and LIS read and responded to the book, raising critical and heuristic questions in the spirit of scholarly dialogue. Floridi responded to these questions. Findings – Floridi’s PI, including (...) this latest publication, is of interest to LIS scholars, and much insight can be gained by exploring this connection. It seems also that LIS has the potential to contribute to PI’s further development in some respects. Research implications – Floridi’s PI work is technical philosophy for which many LIS scholars do not have the training or patience to engage with, yet doing so is rewarding. This suggests a role for translational work between philosophy and LIS. Originality/value – The book symposium format, not yet seen in LIS, provides forum for sustained, multifaceted and generative dialogue around ideas. (shrink)

Thomas Jefferson and Philosophy: Essays on the Philosophical Cast of Jefferson’s Writings is a collection of essays on topics that relate to philosophical aspects of Jefferson’s thinking over the years. Much historical insight is given to ground the various philosophical strands in Jefferson’s thought and writing on topics such as political philosophy, moral philosophy, slavery, republicanism, wall of separation, liberty, educational philosophy, and architecture.

The study zeroed in on the perception of college students who are exposed to sights of poverty in their immediate environment. The student-participants were asked to provide their perception, understanding, and behaviour towards poverty using the photographs that they took on their own. In qualitative research practice, this methodology is called photo elicitation. It was revealed, among others, that the participants have shown negative perceptions about poverty. They strongly felt bad about each photograph that they took and what these images (...) portrayed. The participants visualized their community and thereby weaved analyses and opinions that encroached on various philosophical and sociological theories. There are four interrelated dominant images that were drawn: exteriority image, dirt-poor image, victim-blaming image, and hand-to-mouth image. (shrink)

The essays in this book, by a variety of leading Augustine scholars, examine not only Augustine's multifaceted philosophy and its relation to his epoch-making theology, but also his practice as a philosopher, as well as his relation to other philosophers both before and after him. Thus the collection shows that Augustine's philosophy remains an influence and a provocation in a wide variety of settings today.

Let A be an infinite Δ₂⁰ set and let K be creative: we show that K≤Q A if and only if K≤Q₁ A. (Here ≤Q denotes Q-reducibility, and ≤Q₁ is the subreducibility of ≤Q obtained by requesting that Q-reducibility be provided by a computable function f such that Wf(x)∩ Wf(y)=∅, if x \not= y.) Using this result we prove that A is hyperhyperimmune if and only if no Δ⁰₂ subset B of A is s-complete, i.e., there is no Δ⁰₂ subset (...) B of A such that \overline{K}≤s B, where ≤s denotes s-reducibility, and \overline{K} denotes the complement of K. (shrink)

We prove that if $A$, $B$ are noncomputable c.e. sets, $A<_{sQ_{1}}B$ and [($B$ is not simple and $A\oplus B\leq _{sQ_{1}}B$) or $B\equiv _{sQ_{1}}B\times \omega $], then there exist infinitely many pairwise $sQ_{1}$-incomparable c.e. sets $\{C_{i}\}_{i\in \omega }$ such that $A<_{sQ_{1}}C_{i}<_{sQ_{1}}B$, for all $i\in \omega $. We also show that there exist infinite collections of $sQ_{1}$-degrees $\{\boldsymbol {a_{i}}\}_{i\in \omega }$ and $\{\boldsymbol {b_{i}}\}_{i\in \omega }$ such that for every $i, j,$ (1) $\boldsymbol {a_{i}}<_{sQ_{1}}\boldsymbol {a_{i+1}}$, $\boldsymbol {b_{j+1}}<_{sQ_{1}}\boldsymbol {b_{j}}$ and $\boldsymbol {a_{i}}<_{sQ_{1}}\boldsymbol {b_{j}}$; (...) (2) every c.e set in $\boldsymbol {a_{i}}$ is a maximal set; and (3) every c.e. set in $\boldsymbol {b_{j}}$ is a non-maximal hyperhypersimple set. We prove that a noncomputable c.e. $sQ$-degree contains either only one or infinitely many c.e. $sQ_{1}$-degrees. The $sQ_{1}$-degrees of c.e. cylinders are dense upper semilattice. (shrink)

Let A be an infinite $\Delta _{2}^{0}$ set and let K be creative: we show that K ≤Q A if and only if K ≤Q1 A. (Here ≤Q denotes Q-reducibility, and ≤Q1 is the subreducibility of ≤Q obtained by requesting that Q-reducibility be provided by a computable function f such that Wf(x) ∩ Wf(y) = ∅, if x ≠ y.) Using this result we prove that A is hyperhyperimmune if and only if no $\Delta _{2}^{0}$ subset B of A is (...) s-complete. i.e., there is no $\Delta _{2}^{0}$ subset B of A such that K̄ ≤s B, where ≤s denotes s-reducibility, and K̄ denotes the complement of K. (shrink)

We show that if M is an r‐maximal set, A is a major subset of M, B is an arbitrary set and, then. We prove that the c.e. ‐degrees are not dense. We also show that there exist infinite collections of ‐degrees and such that the following hold: (i) for every i, j,, and,(ii) each consists entirely of r‐maximal sets, and(iii) each consists entirely of non‐r‐maximal hyperhypersimple sets.

We prove that a computably enumerable set A is effectively speedable (effectively levelable) if and only if there exists a splitting (A₀,A₁) of A such that both A₀ and A₁ are effectively speedable (effectively levelable). These results answer two questions raised by J. B. Remmel.

In lieu of an abstract, here is a brief excerpt of the content:131. THE HUME LITERATURE FOR 1978 The Hume Literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; J¿ 5.50), which also lists the main earlier writings on Hume. Publications of the year 1977 were listed in Hume Studies last November. What follows here will bring the record up to the end of 1978. (...) Readers are invited to inform me of any omissions, and to send me offprints of their own articles. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPRevue Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). ANSCOMBE, G. E. M. 'Rules, Rights, and Promises', Midwest Studies in Phil. 3, 318-23. ARMSTRONG, D. M. Universals and Scientific Realism, vol. 2: A Theory of Universals, 85-90. Cambridge. ATTFIELD, R. God and the Secular, esp. chs. 5-6. Cardiff. 132. BAIER, A. 'Hume's Analysis of Pride', JP 75, 27-40. (on Davidson 1976) BALDI, M. 'Le edizioni italiane dei Saggi economici di David Hume', Riv. crit. Stor. FiI. 33, 275-96. BARNOUW, D. 'Skepticism as a Literary Mode - Hume, David and Musil, Robert', Mod. Lang. Notes 93, 852-70. BASU, D. K. 'Who is the Real Hume in the Dialogues?', Indian Phil. Q. 6, 21-8. BEAUCHAMP. see ROBINSON. BECK, L. W. Essays on Kant and Hume. New Haven & London, (includes reprints of his 1967a and b, and 1974, and the first Eng. tr. of his 1969; also a new paper,? Prussian Hume and a Scottish Kant', on pp. Ill ff) BLACKMAN, L. L. 'The Logical Impossibility of Miracles in Hume', Int. J. Phil. Relig. 9, 179-87. BOSS, G. "1I Promise": Les fonctions du langage chez Hume et Austin', Revue Théol. et Phil. 110, 29-48. BRACKEN, H. M. 'Bayle, Berkeley, and Hume', EighteenthCentury Studies 11, 227-45. BROWNSEY, P. F. 'Hume and the Social Contract', PQ 28, 132-48. BURKE, J. J. 'Hume's History of England: Waking the English from a Dogmatic Slumber', Studies in 18th-century Culture 7, 235-50. CAPALDI, N. 'Hume as Social Scientist', RM 32, 99-123. CARNIE, R. H. 'The Hume-Hailes Relationship', Forum for Mod. Lang. Studies 14, 289-303. CARTWRIGHT, N. 'Comments on Wesley Salmon's "Science and Religion..."', Phil. Studies 33, 177-83. COHEN, Benjamin. 'Contrariety and Causality in Hume', Hume Studies 4, 29-39. CONNIFF, J. 'Hume on Political Parties: The Case for Hume as a Whig', Eighteenth-Century Studies 12, 150-73. CUMMINS, R. 'The Missing Shade of Blue', PR 87, 548-65. DOUBLE, R. 'Hume's Empirical Argument for Empiricism', Sth J. Phil. 16, 329-38. 133. ERDE, E. L. 'Founding Morality: "Hume v. Plato" or "Hume & Plato"?', S. -west. J. Phil. 9, 19-25. FARR, J. 'Hume, Hermeneutics, and History: A "Sympathetic" Account', Hist. & Theory 17, 285-310. FLEW, A. 'Inconsistency within a Reconciling Project', Hume Studies 4, 1-6. GASKIN, J. C. A. Hume's Philosophy of Religion, (xi, 188 pp.* London. [Times Higher Ed. Suppl. 21 July (1978), 17; TLS 28 July (1978), 863; RB 20 (1979), 68-71] GINSBERG, R. 'Hume and the Social Contract', EighteenthCentury Life 4, 91-4. GUPTA, G. 'Another Look at the Buddha-Hume "Connection"', Indian Phil. Q. 5, 371-86. GUPTA, R. 'Certain Aspects of the Causal Theories of the Buddhist, Hume and Mill', Indian Phil. Q. 5, 319-35. HAAKONSSEN, K. 'Hume's Obligations', Hume Studies 4, 7-17. HACKING, I. 'Hume's Species of Probability', Phil. Studies 33, 21-37. HALL, R. Fifty Years of Hume Scholarship: A bibliographical guide. (x, 150 pp.) Edinburgh. [British Book News... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:86. THE HUME LITERATURE FOR 1977 In my recently-published book, Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; ^ 5.50), the reader will find a thorough coverage of the Hume literature from 1925 to 1976, with lists of the main earlier writings on Hume, all indexed by author, language, and subject. What follows here will bring the record up to the end of 1977.· Readers (...) are invited to inform me of any omissions. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PBA Proceedings of the British Academy PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard. ÄRDAL, P. S. 'Convention and Value',in G. P. Morice, David Hume, Bicentenary Papers,51-68. Edinburgh. ÁRDAL, P. S. 'Another Look at Hume'sAccount of Moral Evaluation', JHP 15, 405-21. 87. BERK, E.? Note on Hume's Treatise I. iv. 1', Mind 86, 118-19. BERLIN, I. 'Hume and the Sources of German Anti-Rationalism', in Morice, op. cit., 95-116. BERRY, C. J. 'From Hume to Hegel: The Case of the Social Contract', JHI 38, 691-703. BOTWINICK, A.? Case for Hume's Nonutilitarianism', JHP 15, 423-35. BRADLEY, M. C. 'Stove on Hume', Australas. J. Phil. 55, 69-73. BRANDT, R. 'The Beginnings of Hume's Philosophy', in Morice, op. cit., 117-27. BRICKE, J. 'Hume on Self-Identity, Memory and Causality', in Morice, op. cit., 167-74. BRITTON, K. 'Hume on some Non-Natural Distinctions', in Morice, op. cit., 205-9. BURKS, A. W. Chance, Cause, Reason, esp. 128-42 ('Hume's thesis on the justification of induction'). Chicago. CASSIDY, J. 'The Nature of Hume's Inductive Scepticism: A Critical Notice', Ratio 19, 47-54. (on Stove 1973) COHEN, E. D. 'Hume's Fork', Sth. J. Phil. 15, 443-55. CONNON, R. W. 'The Textual and Philosophical Significance of Hume's MS Alterations to Treatise III ', in Morice, op. cit., 186-204. [PQ 28 (1978), 265-8] CONNON, R. W. & POLLARD, M. On the Authorship of "Hume's" Abstract', PQ 27, 60-6. CORSANO, A. 'Vico et Hume face au problème religieux', Archives de Phil. 40, 241-50. DAVIE, G. E. 'Edmund Husserl and "the as yet, in its most important respect, unrecognised greatness of Hume",' in Morice, op. cit., 69-76. DAVIS, J. W. 'Hume on Qualitative Content', in Morice, op. cit., 175-80. DELEULE, D. Hume, Lettre d'un Gentilhomme à son ami d'Edimbourg, présentation, traduction et notes. Paris. (French translation, with facing original, of A Letter from a Gentleman, Edinburgh, 1745) 88. DÉME", N. 'La Méthode Newtonienne et les Lois Empiriques de l'Anthropologie dans Traité II', in Morice, op. cit., 139-45. FORBES, D. 'Hume's Science of Polities', in Morice, op. cit., 39-50. FORCE, J. E. 'Hume in the Dialogues, the Dictates of Convention, and the Millennial Future State of Biblical Prophecy', S. -west. J. Phil. 8, 131-41. GAWLICK, G. 'Hume and the Deists: a Reconsideration', in Morice, op. cit., 128-38. GLOSSOP, R. J. 'In defence of David Hume', Australas. J. Phil. 55, 59-63. GLOUEERMAN, M. 'Hume on Modes', Hume Studies 3, 32-50. GUPTA, B. 'Buddha and Hume: A Popular Comparison Revisited ', Int. Phil. Q. 17 (1977), 135-46. HALL, R. 'The Hume Literature for 1976', Hume Studies 3, 94-102. HEALY,. M. 'Substance and Spiritual Substance - A criticism of David Hume', Alethe ia (Irving, Texas) 1 (1977), 159-83. HEDENIUS, I. Filosofien i ett föränderligt samhälle, 37-59 ( ' Värdeteorierna hos Hume': the value-theories in Hume). Stockholm. HINCKFUSS, I. 'Stove, Induction and the Irish', Australas. J. Phil. 55, 64-8. HISKES... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:429 THE HUME LITERATURE FOR 1985 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. (The book is still in print.) Publications of the years 1977 to 1984 were listed in previous issues of Hume Studies. What follows here will bring the (...) record up to the end of 1985. Readers are invited to inform me of any omissions, and keenly requested to send me offprints of their own articles and reviews. Hardly any do so at present, and it would greatly ease the labour of collection. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of this annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly HPQ History of Philosophy Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement 430 Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). AGASSI, J. "The Unity of Hume's Thought", Hume Studies (10th Anniv. Issue), 87-109. AUSTIN, W. H. "Philo's Reversal", Phil. Topics 13, no. 2, 103-12. BADIA CABRERA, M. A. "Hume's Natural History of Religion: Positive Science or Metaphysical Vision of Religion", Diálogos 20, 71-8. BAIER, A. Postures of the Mind, ch. 10 ("Promises, Promises, Promises"), ch. 11 ("Civilizing Practices"). London, etc. BEHAN, D. P. "Hume's Labyrinth", HPg 2, 309-22. BENNETT, D. "Hume's Pride", in B. Vermazen, Essays on Davidson, 89-91. Oxford. BIRO, J. L. "Hume and Cognitive Science", HPQ 2, 257-74. BLANDINO, G. "Le causalitate. Discussion sur le criticas de D. Hume" [in Interlingua, with French and English], Aquinas 28, 247-57. BRICKE, J. "Locke, Hume and the Nature of Volitions", Hume Studies (10th Anniv. Issue), 15-51. BROOKS, D. "Hume's Bundle Theory of the Mind", S. African J. Phil. 4, 75-84. BROOKS, D. H. M. "Strawson, Hume, and the Unity of Consciousness", Mind 94, 583-6. CAMPBELL, K. "John Passmore and Hume's Moral Philosophy", Hume Studies 11, 109-24. CAPALDI, N. "The Historical and Philosophical Significance of Hume's Theory of the Self", in A.J. Holland, Philosophy, Its History and Historiography, 271-85, Dordrecht, etc. 431 CARLSON, G. R. "Hume and the Moral Realists", Australas. J. Phil. 63, 407-18. CHAKRABARTI, T. K. "Hume's Definitions of Cause", J. Indian Council Phil. Res., 67-75. CHEN, W. -S. Article (in Chinese) on Hume on personal identity, in Phil. Rev. (Taiwan) 8, 123-42. CLARK, S. R. L. "Hume, Animals and the Objectivity of Morals", P£ 35, 117-33. CLERO, J. P. La philosophie des passions chez David Hume. (301 pp.) Paris. DANIEL, S. C "The Problem of Identity of Objects in Hume's Philosophy", Indian Phil. Q. 12, 1916. DAVIE, W. "Hume on Morality, Action, and Character", HPQ 2, 337-48. DEWITT, R. "Hume's Probability Argument of I, iv, 1", Hume Studies 11, 125-40. DONNICI, R. "Husserl sull' etica di Hume. Dalle lezioni inedite del 1902", Rivista di storia della filosofia 40, 449-70. ENC, B. "Hume on Causal Necessity: A Study from the Perspective of Hume's Theory of Passions", HPQ 2, 235-56. FERREIRA, M.J. "Hume's Naturalism - 'Proof and Practice", P£ 35, 45-57. FLAGE, D.E. "Hume on Memory and Causation", Hume Studies (10th Anniv. Issue), 168-88. [11 (1985) 166-72] FLAGE, D.E. "Perchance to Dream: A Reply to Traiger", Hume Studies 11, 173-82. (on Traiger 1985b) FLAGE, D.E. "Hume's Ethics", Phil. Topics 13, no. 3, 71-88. FLEW, A. "Impressions and Experiences: Public or Private?", Hume Studies 11, 183-91. 432 FOGELIN, R.J. Hume's Skepticism... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:192. THE HUME LITERATURE FOR 1983 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1982 were listed in Hume Studies in previous Novembers. What follows here will bring the record up to the end of (...) 1983. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQ American Philosohical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Arisotelian Society PB Philosophical Books PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British standard (no. 4148). 193, ARNOLD, N. S. 'Hume's Skepticism about Inductive Inference', JHP 21, 31-55. BARKER, S. 'Hume on the Logic of Design', Hume Studies 9, 1-18. [19-24] BERMAN, D. 'David Hume and the Suppression of Atheism', JHP 21, 375-87. BOX, M.? Gloss on Goldsmith's Remark on Hume', Notes & Queries 30, 59-60. BRETT, N. 'Hume's Debt to Kant', Hume Studies 9, 5973. BROUGHTON, J. 'Hume's Skepticism about Causal Inference', Pacific phil. Q. 64, 3-18. CALVERT, B. 'Another Problem about Part IX of Hume's Dialogues', Int. J. Phil. Relig. 14, 65-70. COLWELL, G.G. 'Miracles and History', Sophia 22, 9-14. DARWALL, S. L. Impartial Reason, ch. 5 ('Hume's Internalism1 ). Ithaca, N. Y. DEL VECCHIO, M. 'Un Impotesi di Lettura Esegetlica del "Dubbio Scettico" Humeano', Riv. crit. Stor. FiI. 38, 457-64. FOGELIN, R. J. 'The Tendency of Hume's Skepticism', in M. Burnyeat, The Skeptical Tradition, 397-412. Berkeley, CaI. GASKIN, J. CA. 'Hume's Attenuated Deism', Arch. Gesch. Phil. 65, 160-73. GEMES, K.? Refutation of Inductive Scepticism', Australas. J. Phil. 61, 434-8. GUTTENPLAN, S. 'Hume and Contemporary Ethical Naturalism', Midwest Stud. Phil. 8, 309-20. HARRIS, H. S. 'Hume and Barker on the Logic of Design', Hume Studies 9, 19-24. HARTSHORNE, C 'Hume's Metaphysics and its Influence', in C Hartshorne, Insights and Oversights of Great Thinkers, 136-50. HIRSCH, E. 'Hume's Distinction between Genuine and Fictitious Identity', Midwest Stud. Phil. 8, 321-38. 194, IMMERWAHR, J. 'David Hume, Sexism, and Sociobiology ', Sth. J. Phil. 21, 359-70. KIVY, P. 'Hume's Neighbour's Wife: An Essay on the Evolution of Hume's Aesthetics', Br. J. Aesth. 23, 195-208. KUEHN, M. 'Kant's Conception of "Hume's Problem"', JHP 21, 175-93. KUEHN, M. 'Hume's Antinomies', Hume Studies 9, 25-45. McCRACKEN, CJ. Malebranche and British Philosophy, ch. 7. Oxford. McLYNN, F.J. 'Jacobitism and David Hume: The Ideological Backlash Foiled', Hume Studies 9, 171-99. MALHERBE, M. 'La notion de circonstance dans la philosophie de Hume', Hume Studies 9, 130-49. NATHAN, G. J.? Humean Pattern of Justification', Hume Studies 9, 150-70. NIELSEN, K. 'Hobbesist and Humean Alternatives to a Religious Morality', Int. J. Phil. Relig. 14, 33-47. PENELHUM, T. 'Natural Belief and Religious Belief in Hume's Philosophy', P£ 33, 166-81. [182-6] PONKO, T. A. 'Artificial Virtue, Self-interest, and Acquired Social Concern', Hume Studies 9, 4658. ROD, W. 'The Rationalist Theory of Double Causality as an Object of Hume's Criticism', Erkenntnis 19, 315-29. ROHATYN, D. 'Hume's Dialectical Conceits: The Case of Dialogue XII', Phil. & phenomenol. Res. 43, 519-32. RUSSELL, P. 'On the Naturalism of Hume's "Reconciling Project"', Mind 92, 593-600. SCARRE, G. 'What was Hume's worry about Personal Identity?', Analysis 43, 217-21. SCARRE, G. 'Was Mill Really Concerned with Hume's Problem of... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:167 THE HUME LITERATURE FOR 1982 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1981 were listed in Hume Studies in previous Novembers. What follows here will bring the record up to the end of (...) 1982. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPRevue Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). 168 AIKEN, H. D. 'The Originality of Hume's Theory of Obligation', Phil. & Phenomenol. Res. 42, 374-83. BADIA CABRERA, M. A. 'Milagro, testimonio y verdad. El significado de la crítica de Hume', Dialogos (Puerto Rico) 17, 37-52. BAIER, A. 'Hume's Account of our Absurd Passions', JP_ 79, 643-51. [652] BARON, M. 'Hume's Noble Lie: An Account of his Artificial Virtues', Can. J. Phil. 12, 539-55. BERRY, CJ. Hume, Hegel and Human Nature, pt. 2 (55124 ). The Hague, etc. [Hume Studies 9 (1983) 200-3] BERRY, CJ. 'Hume on Rationality in History and Social Life', History & Theory 21, 234-47. BUNZL, M. 'Humean Counterfactuals', JHP 20, 171-7. CALLICOTT, J. B. 'Hume's Is/Ought Dichotomy and the Relation of Ecology to Leopold's Land Ethic', Environmental Ethics 4, 163-74. CAPALDI, N., KING, J. & LIVINGSTON, D. 'The Hume Literature of the 1970s', Philosophical Topics 12, no. 3, 167-92. COLWELL, G.G. 'On Defining Away the Miraculous', Philosophy 57, 327-37. DAVIES, B. An Introduction to the Philosophy of Religion, 52-9 and 108-18. Oxford. DEL BARCO COLLAZOS, J. L. 'Evidencia y verdad en la epistemologia de Hume', Anuario filosófico 15, 175-84. DEL BARCO COLLAZOS, J. L. 'La teoría de la impresión en Hume', Anuario filosofico 15, 85-112. DRAPER, T. 'Hume and Madison: The Secrets of Federalist Paper No. 10', Encounter 58, (Feb.) 34-47. FARR, J. 'Humean Explanations in the Moral Sciences', Inquiry 25, 57-80. FERN, R. L. 'Hume's Critique of Miracles: An Irrelevant Triumph', Relig. Studies 18, 337-54. FITZPATRICK, J. 'Lonergan and Hume [I-IV: various aspects]', New Blackfriars 63, 122-30, 219-28, 275-86, 364-72. 169 FLAGE, D.E. 'Relative Ideas Revisited: A Reply to Thomas', Hume Studies 8, 158-71. FLAGE, D.E. 'Hume's Dualism', Nous 16, 527-41. FLEW, A. 'Another Idea of Necessary Connection', Philosophy 57, 487-94. FLEW, A. '"Hume on Space and Geometry": One Reservation ', Hume Studies 8, 62-5. [66-9] FORBES, D. 'Natural Law and the Scottish Enlightenment', in R. H. Campbell & A. S. Skinner, The Origins and Nature of the Scottish Enlightenment, 186204. Edinburgh. FORCE, J. E. 'Hume and Johnson on Prophecy and Miracles: Historical Context', JH_I 43, 463-75. FRIEMAN, J. 'Boswell Confronts Hume: An Encounter with the Great Infidel', Free Inquiry 2, 22-5. GALGAN, G.J. The Logic of Modernity, 118-36 ('Hume: The Breakdown of Certitude'). New York S London. HALL, R. 'The Hume Literature for 1981', Hume Studies 8, 172-7. HALLER, R. Urteile und Ereignisse, 76-85 ('Humes Analyse'). Munich. HAUSMAN, A. 'It Ain't Necessity, So... (with Apologies to George Gershwin)', Hume Studies 8, 87-101. HILL, E. 'Hume and the Delightful Tragedy Problem', Philosophy 57, 319-26. HOERSTER, N. 'David Hume', in N. Hoerster, Klassiker des philosophischen Denkens, vol. 2, 7-46. Munich. JONES, G. E. 'Vindication, Hume and Induction', Can. J. Phil. 12, 119-29. JONES, P. 'Laughter', PAS... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:172. THE HUME LITERATURE FOR 1981 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; jê9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1980 were listed in Hume Studies for the last four Novembers. What follows here will bring the record up to (...) the end of 1981. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPReview Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly fol· low the British Standard (no. 4148). BAGOLINI, L. 'Legal Obligation in Hume', Hume Studies 7, 85-93. BAIER, A. 'Frankena and Hume on Points of View', The Monist 64, 342-58. BATTERSBY, C. 'An Enquiry concerning the Humean Woman', Philosophy 56, 303-12. 173. BEAUCHAMP, T. L. & ROSENBERG, A. Hume and the Problem of Causation, (xxv, 340 pp.) New York. [PB 23 (1982) 129-48 (Mackie, Flew, Beauchamp & Rosenberg) ] BOTWINICK, A. 'Hume on Is-Ought', Auslegung 8, 19-30. BURNS, R. M. The Great Debate on Miracles, esp. chs. 6-8. Lewisburg, London & Toronto. COSTA, M. J. 'Hume and Justified Belief, Can. J. Phil. 11, 219-28. CRONIN, R. Shelley's Poetic Thoughts, 77-83. London. DE MARTELAERE, P. 'Hume's "Gematigd" Scepticisme: Futiel of Fataal', Tijdschrift voor Filosofie 43, 427-64. DILMAN, I. Studies in Language and Reason, chs. 4-5. London. FARR, W. Hume and Kant: Studienbuch zum Erkenntsnisproblem. (250 pp.) Freiburg & Munich. FEINSTEIN, R. 'Some Problems in Humean Philosophy', Ind. phil. Q. 8, 527-32. FLAGE, D. E. 'Hume's Relative Ideas', Hume Studies 7, 55-73. GARCIA ROCA, J. Positivismo e Ilustración : La filosofía de David Hume. (304 pp.) Valencia. GARRETT, D. 'Hume's Self-Doubts about Personal Identity', PR 90, 337-58. GUPTA, B. 'Scepticism: Ancient "East" and Modern "West"', Ind. phil. Q. 9, 29-44. HAAKONSSEN, K. The Science of a Legislator, the Natural Jurisprudence? of David Hume and Adam Smith. Cambridge. HALL, R. 'The Hume Literature for 1980', Hume Studies 7, 184-90. íiARRISON, J. Hume's Theory of Justice. (xxvi, 304 pp.) Oxford. [THES no. 440 (3 Apr. 1981) 15] IMLAY, R. A. 'Hume's Of Scepticism with regard to reason: A Study in Contrasting Themes', Hume Studies 7, 121-36. JOHNSON, 0. A. 'Hume's "True" Scepticism', Pacific phil. Q. 62, 403-10. JONES, G. E. 'Vindication, Hume, and Induction', Can. J. Phil. 12, 119-29. 174. KING, J. 'Hume's Classical Theory of Justice', Hume Studies 7, 32-54. KULENKAMPFF, J. 'David Hume (1711-1776)', in 0. Hoffe, Klassiker der Philosophie, vol. 1, 434-56. Munich. LOEB, L. E. From Descartes to Hume, sec. 39 (354-63). Ithaca & London. MACLEOD, A. "Rule-Utilitarianism and Hume's Theory of Justice', Hume Studies 7, 74-84. MAHER, P. 'Probability in Hume's Science of Man', Hume Studies 7, 137-53. MALHERBE, M. 'Les études humiennes: anatomie et problèmes1, Archives de Philosophie 44, 637-71. MILLER, D. Philosophy and Ideology in Hume's Political ThoughtT (218 pp.) Oxford. [London Rev, of Bks 4 (1982), no. 7, 22-4; PB 23 (1982) 206-9] MONTEIRO, J. P. 'Hume's Conception of Science', JHP 19, 327-42. NEWMAN, R. 'Hume on Space and Geometry', Hume Studies 7, 1-31. NIELSON, H. A. 'Inference and Experience in Hume's Enquiry', Phil. Res. Archives 7, no. 1471. NORTH, T. 'What if I'm Indifferent?', Phil. Investigations 4, 24-37. PAPPAS, G. S. 'On McRae's Hume', Hume Studies... (shrink)

A comprehensive reference work for everyone concerned with the complicated moral issues of this world, this unique volume clearly communicates what Scripture teaches about the ethical dilemmas facing our society. Biological warfare, corporate responsibility, human rights, computer ethics, and much more are discussed by over fifty scholars who explain the moral guidelines in the Bible and historic Christian teachings. R.K. Harrison, author and editor of over thirty books on biblical studies, has brought together a valuable A to B treasury of (...) thought for every believer searching for guidance. (shrink)

The complex-systems approach to cognitive science seeks to move beyond the formalism of information exchange and to situate cognition within the broader formalism of energy flow. Changes in cognitive performance exhibit a fractal (i.e., power-law) relationship between size and time scale. These fractal fluctuations reflect the flow of energy at all scales governing cognition. Information transfer, as traditionally understood in the cognitive sciences, may be a subset of this multiscale energy flow. The cognitive system exhibits not just a single power-law (...) relationship between fluctuation size and time scale but actually exhibits many power-law relationships, whether over time or space. This change in fractal scaling, that is, multifractality, provides new insights into changes in energy flow through the cognitive system. We survey recent findings demonstrating the role of multifractality in (a) understanding atypical developmental outcomes, and (b) predicting cognitive change. We propose that multifractality provides insights into energy flows driving the emergence of cognitive structure. (shrink)